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October 1970


Author Affiliations

Kingston, Ontario, Canada

Arch Otolaryngol. 1970;92(4):411-412. doi:10.1001/archotol.1970.04310040099023

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To the Editor.  —My associates and I have been studying the biochemistry, physiology, and pharmacology of respiratory tract fluid for over 30 years. I did not attempt to review this work in the paper on inhaled oil of nutmeg but did refer to reviews in papers listed as reference numbers 1, 2, 5, and 6. Available evidence on factors which control the rate of production and composition is noted in the references cited. Like most research problems, this is a never-ending field and I am discussing a new factor, the effect of body temperature on respiratory tract fluid, at the annual meeting of the Canadian Society of Chemotherapy at Quebec City in May 1970.Body temperature is an important factor because air inhaled by anesthetized laboratory animals arranged for the collection of respiratory tract fluid has to be warmed to body temperature and saturated with water vapor. Respiratory tract

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