The Stevens-Johnson syndrome is a skin disease that includes oral and eye manifestations. The oral aspect of the disease may predominate which makes the diagnosis difficult. The oral lesions do not occur simultaneously and each lesion's life cycle can be classified into five stages. The eye involvement is usually limited to the conjunctiva, although much more severe ocular forms can occur. When this disease is limited to the oral cavity it is usually confused with herpes simplex. The etiology is unknown, and since it is almost always self-limited, the treatment is supportive.
Calcaterra TC, Strahan RW. Stevens-Johnson Syndrome: Oropharyngeal Manifestations. Arch Otolaryngol. 1971;93(1):37–41. doi:10.1001/archotol.1971.00770060069007
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