Six cases of a rare clinical entity called angiomatosis of the tongue are presented. The term diffuse angiomatosis is preferred since the major portion of the tongue is involved and the individual lesions may be composed of blood or lymphatic vessels, or both. Macroglossia, pink to purple papillary projections, and episodes of hemorrhage occurred in all cases. Extensive involvement of the tongue with vascular hamartomatous lesions often presents a bizarre, confusing clinical picture. Adequate therapy for this condition is not possible until the true nature of the lesion is disclosed. Various types of treatment are discussed and a rational approach to therapy is presented.
Giunta J, Shklar G, McCarthy PL. Diffuse Angiomatosis of the Tongue. Arch Otolaryngol. 1971;93(1):83–89. doi:10.1001/archotol.1971.00770060115018
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.