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January 1971

Caffey's Disease

Author Affiliations

St. Louis
From the Department of Otolaryngology, Washington University School of Medicine, St. Louis.

Arch Otolaryngol. 1971;93(1):98-100. doi:10.1001/archotol.1971.00770060130021

Caffey's disease (infantile cortical hyperostosis) presents in infants and is characterized by hyperirritability, fever, and cortical hypertrophy of the bone with overlying soft tissue swelling. The disease is a nonspecific embryonal osteodysgenesis; a familial tendency has been noted. Differential diagnosis is not difficult. Therapy is supportive and the prognosis generally good. Otolaryngologists encounter this disease in the mandible and in several other sites about the skull and face.

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