Caffey's disease (infantile cortical hyperostosis) presents in infants and is characterized by hyperirritability, fever, and cortical hypertrophy of the bone with overlying soft tissue swelling. The disease is a nonspecific embryonal osteodysgenesis; a familial tendency has been noted. Differential diagnosis is not difficult. Therapy is supportive and the prognosis generally good. Otolaryngologists encounter this disease in the mandible and in several other sites about the skull and face.
Bone RC. Caffey's Disease. Arch Otolaryngol. 1971;93(1):98–100. doi:10.1001/archotol.1971.00770060130021
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