The significance of enlarged salivary glands in diabetes is not clear. The present study was concerned with the possible relationship of the submaxillary glands to glucose tolerance. No significant difference in blood glucose concentrations at any time interval following intravenous glucose administration was observed after removal of the submaxillary glands. Similarly, plasma immunoreactive insulin (IRI) concentrations following intravenous glucose administration were not significantly altered after submaxillary gland removal. Thus, it appears that the normal submaxillary glands do not play a significant role in glucose and insulin homeostasis in the dog.
Garcia AR, Blackard WG, Trail ML. Submaxillary Gland Removal: Effects on Glucose and Insulin Homeostasis. Arch Otolaryngol. 1971;93(6):597–598. doi:10.1001/archotol.1971.00770060899009
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