[Skip to Navigation]
June 1971

Middle and Inner Ear Abnormalities: 13-15 (D1) Trisomy

Author Affiliations

From the Division of Otolaryngology, Department of Surgery, University of Colorado Medical Center, Denver. Dr. Black is currently on military leave of absence at the Naval Hospital, Philadelphia.

Arch Otolaryngol. 1971;93(6):615-619. doi:10.1001/archotol.1971.00770060917013

Temporal bone findings from the study of a patient afflicted with trisomy 13-15 syndrome included multiple anomalies of the middle ear structures derived from the second branchial arch and abnormalties of the otic capsule. A shortened but otherwise well-formed Corti's organ was situated in a distorted and incompletely developed bony cochlea. Cochlear hair cells were sufficiently well preserved to allow mapping. The complement of hair cells present in these temporal bones contrasts with some previously reported findings.