The giant cell tumor of bone is a rare entity in bones of the head and neck. There is little established precedent for its treatment in this area. Management of a case and an analysis of 13 other reported cases suggests that diagnostic bioposy of the lesion followed by cobalt 60 radiotherapy achieves the most favorable results.
Emley WE. Giant Cell Tumor of the Sphenoid Bone: A Case Report and Review of the Literature. Arch Otolaryngol. 1971;94(4):369–374. doi:10.1001/archotol.1971.00770070561016
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