The increasing use of aspirin in the 71 years since its rediscovery has been paralleled by an increasing number of reports of its toxic effects. Many of these effects are of particular importance to the otolaryngologist since they involve the ear, respiratory tract, upper gastrointestinal tract, and hemostatic mechanisms. In many instances of aspirin toxicity, the clinical symptoms and signs can be traced to cellular or subcellular phenomena.
Lucente FE. Aspirin and the Otolaryngologist. Arch Otolaryngol. 1971;94(5):443–446. doi:10.1001/archotol.1971.00770070689010
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