Mongrel dogs were randomly divided into 2 groups. In the first group, cervical esophageal reconstruction was accomplished utilizing nonrevascularized jejunal autograft. In the second group, irradiated horse vein was used as a heterograft. In both groups, the grafts became necrotic and acted as a stroma for the ingrowth of a dense vascular scar, which became lined by a stratified squamous mucosa. Strictures were the only uniform complication. They were soft and easy to dilate. Long-term survivors did well on a soft diet and infrequent dilations.
Stoner JC, Thomas GK, Albo DC. Cervical Esophageal Replacement: Use of Nonrevascularized Jejunum and Irradiated Horse Vein. Arch Otolaryngol. 1972;95(2):141–145. doi:10.1001/archotol.1972.00770080229010
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: