Two groups of Holtzman albino rats were given fluoridated water (5.0 ppm) and nonfluoridated water (0.0 ppm), respectively, and the microgram of fluoride and calcium in the stapes at 21, 52, and 150 days of age in each group were then analyzed. Significant differences were found within and between the groups.
Daniel HJ, Simpson EC, LeDoux JC. Fluoride and Calcium Content of the Rat Stapes. Arch Otolaryngol. 1972;95(3):265–268. doi:10.1001/archotol.1972.00770080407014
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: