Classical hemophilia results from a total or partial deficiency of AHG or antihemophiliac globulin (factor VIII). By the addition of this factor to the blood, the clotting mechanism will become normal. Modern management requires the use of concentrates of AHG to prevent circulatory overload previously resulting from massive transfusions. Close cooperation with the hematologist is required if elective surgery is to be safely performed.
Weissman BW, Panettiere F. Hemophilia in Otolaryngology: Current Concepts. Arch Otolaryngol. 1972;95(6):526–529. doi:10.1001/archotol.1972.00770080816006
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