The safety of a 50-mw round window ultrasonic irradiation was evaluated in cats. The largest temperature rise of 8 C occurs in the coupling water in the round window niche. The temperature in the perilymph in the vestibule is increased by 3 C while the temperature of the facial nerve rises by only 1 C. The osseous lamina does not appreciably alter the path of the ultrasonic beam and no significant changes were observed in cochlear microphonics at frequencies up to 14 kilohertz following the irradiation.
Kossoff G. Safety Factors of the Ultrasonic Round Window Irradiation Technique. Arch Otolaryngol. 1972;96(2):113–116. doi:https://doi.org/10.1001/archotol.1972.00770090187004
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