Twelve patients with nasopharyngeal angiofibroma who initially complained of nasal obstruction were treated. Eight patients experienced epistaxis, and in three the condition was serious. The tumor extended beyond the nose and nasopharynx in ten patients. Roentgenographic examinations including selective carotid arteriography confirmed the diagnosis and revealed the tumor's size, its extensions, and its feeding vessel.
All patients underwent surgical excision through a transpalatal incision with compression of the external carotid artery and freezing with the Cooper cryoprobe. Blood losses for invasive tumors averaged 1,050 ml, for noninvasive tumors 525 ml. The blood loss for all 12 patients averaged 1,166 ml. Nine patients have been observed for more than two years, and none of them have persistent or recurrent tumors. Three patients observed for more than six months, but less than two years, have no evidence of disease.
English GM, Hemenway WG, Cundy RL. Surgical Treatment of Invasive Angiofibroma. Arch Otolaryngol. 1972;96(4):312–318. doi:10.1001/archotol.1972.00770090488003
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