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January 1973

Histopathology of Otosclerosis

Arch Otolaryngol. 1973;97(1):24-29. doi:10.1001/archotol.1973.00780010028008

The histopathologic features of otosclerosis as observed by light microscopy in a series selected from some 90 bones with otosclerosis are presented. The cases selected represent two types or stages of the disease. Examples of a solitary focus of histologic nonclinical otosclerosis in each of the areas of greatest predilection are shown.

A second series of cases has been selected in which sensorineural hearing loss has occurred as a complication of the otosclerotic process. In all definitive cases there has been ankylosis of the stapes as well with a history of a conduction deafness preceding the sensorineural element. One case with a solitary otosclerotic focus at the round window and sensorineural hearing impairment illustrated the possibility of a relationship.