Studies of serially sectioned operative specimens removed at laryngectomy or pharyngolaryngectomy have revealed the mechanism by which the thyroid gland may be invaded by tumors arising in these structures.
Invasion of the thyroid cartilages and metastatic spread to the prelaryngeal or upper paratracheal nodes may lead to direct invasion of the gland or its isthmus. Total thyroidectomy is essential when resecting postcricoid or subglottic cancers. Partial thyroidectomy with frozen section control is indicated when operating on anterior commissure lesions.
Harrison DFN. Thyroid Gland in the Management of Laryngopharyngeal Cancer. Arch Otolaryngol. 1973;97(4):301–302. doi:10.1001/archotol.1973.00780010311001
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: