Malignant melanoma at present seems to be incurable when it arises in the nasal or sinus cavities. However, we are able to provide a longer and more comfortable life expectancy by constant surveillance and treatment.
Surgery seems to be the treatment of choice. Although ineffective for cure, radiation may play a role in the treatment of inoperable recurrences and help to prolong life. The risk of death by melanoma is constant throughout the course of the disease. Recognition of recurrence or metastasis and effective treatment of it do lengthen survival.
Harvey M. Freedman, Lawrence W. DeSanto, Kenneth D. Devine, Louis H. Weiland. Malignant Melanoma of the Nasal Cavity and Paranasal Sinuses. Arch Otolaryngol. 1973;97(4):322–325. doi:10.1001/archotol.1973.00780010332008