Verrucous carcinoma is a type of epidermoid carcinoma usually found in the oral cavity. It is locally invasive but rarely metastasizes. Since it resists radiation therapy, wide local excision is the treatment of choice.
Pathologic specimens show a thick epithelial surface with normal maturation, an intact basement membrane, and deep, wide rete pegs. These features make it necessary to perform an incisional biopsy for proper diagnosis of this tumor. A case of verrucous carcinoma of the pyriform sinus is presented.
Thomas JR, Snyderman SC, Giffin CS, Goin DW. Verrucous Carcinoma of the Pyriform Sinus. Arch Otolaryngol. 1973;97(6):488–489. doi:10.1001/archotol.1973.00780010502014
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