This was a retrospective study of carcinoma of the larynx presenting statistics on age, sex, race, smoking, and duration and type of symptoms. Pathological staging and clinical staging were compared. Special attention was paid to recurrence of tumor after radiation and subsequent salvage by surgery.
The complication rate was 39% if patients treated by radiation alone were excluded.
The cure rate with primary treatment and over all cure rate, which included secondary treatment were compared: (1) stage 1, 73.2% and 88%; (2) stage 2, 56.5% and 68.5%; (3) stage 3, 22% and 33%; (4) stage 4, 16% and 22%. Of 114 cures, 22 were salvages. Of the 22 salvages, 20 were by surgery and two were by radiation.
Louis D. Lowry, James E. Marks, William J. Powell. 260 Laryngeal CarcinomasStaging and End Results. Arch Otolaryngol. 1973;98(3):147–151. doi:10.1001/archotol.1973.00780020155002