The cochleas of 24 surviving guinea pigs were exposed to continuous-wave argon laser irradiation for periods of one half to three seconds at power densities between 1 and 2 kw/sq cm. The stria vascularis was stained by the peroxidase-benzidine method and studied by light microscopy in acute and long-term animals. Well-defined and reproducible lesions with a width of 50μm to 300μm were observed. The acute changes consisted of central coagulation necrosis as well as surrounding zones of reversible and irreversible damage. The long-term animals showed capillary fibrous strands adjacent to an area of completely destroyed, unregenerated stria vascularis.
Sugar JO, Stahle J, Högberg L. Laser Irradiation of the Stria Vascularis. Arch Otolaryngol. 1974;99(5):330–336. doi:10.1001/archotol.1974.00780030342004
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