Three boys had chloromas arising in the head. Their cases show the different stages of disease that can be present when such a diagnosis is made.
Any tumor of the face can be a manifestation of an underlying hematologic disorder. Thorough examination of the peripheral blood and bone marrow should be made before any extensive surgical procedure is undertaken. The interdisciplinary conference is particularly important in the management of childhood cancer and leukemia since major advances have been made employing multimodal therapy.
Brooks HW, Evans AE, Glass RM, Pang EM. Chloromas of the Head and Neck in Childhood: The Initial Manifestation of Myeloid Leukemia in Three Patients. Arch Otolaryngol. 1974;100(4):306–308. doi:https://doi.org/10.1001/archotol.1974.00780040316014
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