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October 1974

Chloromas of the Head and Neck in Childhood: The Initial Manifestation of Myeloid Leukemia in Three Patients

Author Affiliations

From the departments of pediatrics (Drs. Brooks and Evans) and ophthalmology (Dr. Glass), University of Pennsylvania, Philadelphia, and the Department of Pediatrics, Wyler Children's Hospital, University of Chicago (Dr. Pang).

Arch Otolaryngol. 1974;100(4):306-308. doi:10.1001/archotol.1974.00780040316014

Three boys had chloromas arising in the head. Their cases show the different stages of disease that can be present when such a diagnosis is made.

Any tumor of the face can be a manifestation of an underlying hematologic disorder. Thorough examination of the peripheral blood and bone marrow should be made before any extensive surgical procedure is undertaken. The interdisciplinary conference is particularly important in the management of childhood cancer and leukemia since major advances have been made employing multimodal therapy.