Histiocytosis X may have a variety of clinical manifestations. The otolaryngologist commonly sees patients with this condition because of purulent aural drainage. A patient was referred to the otolaryngology service with enlargement of the submandibular salivary gland. Excision of this unusual site of involvement provided the initial diagnosis of this patient's disease.
Lulenski GC, Singleton EF, Oberman HA. Histiocytosis X: An Unusual Cause of Salivary Gland Enlargement. Arch Otolaryngol. 1974;100(4):319–321. doi:10.1001/archotol.1974.00780040329018
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