Anesthesia of the tympanic membrane and ear canal by the use of iontophoresis of local anesthetics is a painless and safe method of anesthesia for office myringotomy and polyethylene tube insertion, and possibly for surgical use as well.
With the use of guinea pig models, the introduction of 4% lidocaine hydrochloride solution in the middle ear space with iontophoresis revealed no toxic effects on the eighth nerve, and epinephrine hydrochloride potentiates the effects of lidocaine and has no protective mechanism on the eighth nerve function.
Echols DF, Norris CH, Tabb HG. Anesthesia of the Ear by Iontophoresis of Lidocaine. Arch Otolaryngol. 1975;101(7):418–421. doi:10.1001/archotol.1975.00780360018004
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: