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July 1975

Production of Parathyroid Hormone by Laryngeal Cancer: Report of a Case

Author Affiliations

From the departments of otolaryngology (Drs. Saberman and Ross) and hematology and oncology (Dr. Richman), Brookside Hospital, San Pablo, Calif.

Arch Otolaryngol. 1975;101(7):453-454. doi:10.1001/archotol.1975.00780360053012

Nonparathyroid humoral hypercalcemia is becoming an increasingly more common problem associated with carcinoma. Carcinomas of the head and neck may elaborate parathormone or parathormone-like humors that in the absence of bone metastases, renal disease, parathyroid tumors, or secondary hyperparathyroidism may produce hypercalcemia, which if unrecognized, complicates and prevents the appropriate management of the patient.

This report deals with the production of parathyroid hormone and the first reported case, to our knowledge, of carcinoma of the larynx associated with nonparathyroid hypercalcemia.