Several substances are known to have a profound effect on both the kidney and the inner ear. The aminoglycoside antibiotics are toxic to both of these organs. Ethacrinic acid and furosemide affect transport mechanisms in the loop of Henle as well as the inner ear. In addition, studies have suggested antigenic similarities between the stria vascularis of the cochlea and the renal tubules.
This report of potassium bromate poisoning and its resultant deafness and renal failure further emphasizes the curious relationship between these two organ systems.
Quick CA, Chole RA, Mauer SM. Deafness and Renal Failure Due to Potassium Bromate Poisoning. Arch Otolaryngol. 1975;101(8):494–495. doi:10.1001/archotol.1975.00780370036013
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