• Myasthenia gravis, focal to the larynx, should be considered in the differential diagnosis of intermittent breathy dysphonia and aphonia. A 20-year-old woman had intermittent breathy dysphonia and aphonia as the sole manifestation of myasthenia gravis. The vocal cords were flaccid, and adducted to the paramedian position for phonation. Improvement of laryngeal function was demonstrated with edrophonium and neostigmine bromide. Therapy with pyridostigmine bromide (Mestinon) maintained normal phonation.
(Arch Otolaryngol 101:569-570, 1975)
Neiman RF, Mountjoy JR, Allen EL. Myasthenia Gravis Focal to the Larynx: Report of a Case. Arch Otolaryngol. 1975;101(9):569–570. doi:10.1001/archotol.1975.00780380047012
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