• An analysis of 227 consecutive tympanomastoidectomies was undertaken to compare the types and degree of middle ear pathologic features that are found behind central perforations as compared with attic or marginal perforations. In this series, little difference was found between the two groups. A great deal of disease occurred behind all types of tympanic membrane perforations. Near-normal audiogram results did not guarantee a normal middle ear. Central perforations are not necessarily safe and should be treated with the same caution as attic or marginal perforations.
(Arch Otolaryngol 101:626-627, 1975)
Rice DH. Central Perforations—Safe or Unsafe? Arch Otolaryngol. 1975;101(10):626–627. doi:10.1001/archotol.1975.00780390040010
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