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October 1975

Synovial Sarcoma of the Laryngopharynx

Author Affiliations

From the departments of otolaryngology (Dr Gatti) and pathology (Dr Orfei), Loyola University Medical Center, Maywood, Ill, and the Department of Otolaryngology, Naval Regional Medical Center, Oakland, Calif (Dr Strom).

Arch Otolaryngol. 1975;101(10):633-636. doi:10.1001/archotol.1975.00780390047013

• Synovial sarcoma of the laryngopharynx is an extremely rare neoplasm. To date, only two such cases have been reported. We describe two additional patients in whom this lesion occurred as a primary neoplasm of the laryngopharynx. Hoarseness, upper respiratory distress, and dysphagia characterize the original complaints in laryngopharyngeal synovial sarcoma. The difficulties that may be encountered in histologic diagnosis are emphasized. Our findings suggest that an aggressive surgical approach is indicated. Adjuvant therapy with irradiation and the chemotherapeutic agent, doxorubicin (Adriamycin), may contribute to better survival rates.

(Arch Otolaryngol 101:633-636, 1975)

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