• The mucociliary function of the Eustachian tube was assessed in 44 patients with dry perforations of the tympanic membrane by means of the saccharin test. A saccharin crystal was placed on the mucous membrane of the middle ear as close to the orifice of the Eustachian tube as possible, and the time taken for the patient to taste the saccharin was measured. The function of the Eustachian tube was also assessed by means of the aspiration test and by the Valsalva maneuver.
No relationship was found between the results of the saccharin test, aspiration test, and the Valsalva maneuver. However, a correlation seems to exist between the hearing improvement obtained as determined by the postoperative air-bone gap, the positive or negative results of the saccharin test, and (in cases with positive saccharin test) the saccharin perception time.
(Arch Otolaryngol 102:539-541, 1976)
Elbrønd O, Larsen E. Mucociliary Function of the Eustachian Tube: Assessment by Saccharin Test in Patients With Dry Perforations of the Tympanic Membrane. Arch Otolaryngol. 1976;102(9):539–541. doi:10.1001/archotol.1976.00780140071007
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