• Fifteen adults, hospitalized for fiberoptic endoscopy studies, were tested under two conditions using impedance audiometry. The first series of tests was conducted prior to the fiberoptic studies and sedation; the second immediately following examination, approximately 20 minutes after sedation with diazepam (Valium) and meperidine (Demerol) hydrochloride.
Sedation with diazepam and meperidine failed to have a significant effect on tympanometry, static compliance, or differential loudness. These drugs were therefore considered effective sedatives for conducting impedance studies on difficult-to-test patients. This procedure is not recommended as a routine procedure and should be done only as a last resort.
(Arch Otolaryngol 103:235-237, 1977)