• Paragangliomas (chemodectomas, glomus jugulare tumors) represented 15% of all neoplasms of the ear in the period from 1964 to 1975 at the University of Minnesota, Minneapolis. Women in the fifth to sixth decades of life were mainly affected, and hearing loss and tinnitus were the principal symptoms. Although most tumors had the typical histopathologic appearance, two neoplasms that were initially diagnosed as paragangliomas illustrated the problems in differential diagnosis. One of these latter two tumors had metastasized and was thought to represent a malignant paraganglioma. Retrospectively, both neoplasms were adenomatous tumors of the middle ear. For the remaining patients with typical jugular paragangliomas, surgery and/or irradiation therapy controlled the local tumor in 12 cases. Two of the three meningiomas occurring in the middle ear were preceded by or associated with an intracranial component. There were only four prior examples in the literature, excluding our one case, of primary meningiomas of the ear-mastoid region. Histologically, the features were virtually identical to the usual intracranial meningioma.
(Arch Otolaryngol 104:253-259, 1978)
Chen KTK, Dehner LP. Primary Tumors of the External and Middle Ear: II. A Clinicopathologic Study of 14 Paragangliomas and Three Meningiomas. Arch Otolaryngol. 1978;104(5):253–259. doi:10.1001/archotol.1978.00790050019004
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.