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August 1978

Nasal Septal Perforation: A Complication of Nasal Continuous Positive Airway Pressure

Author Affiliations

From the Department of Pediatrics, Division of Neonatology, Cook County Hospital (Drs Yeh, Srinivasan, and Pildes), and the Abraham Lincoln School of Medicine, University of Illinois College of Medicine, Chicago (Drs Yeh and Pildes).

Arch Otolaryngol. 1978;104(8):473. doi:10.1001/archotol.1978.00790080055016

• We report a case of nasal septal perforation in a premature infant. The infant weighed 820 g and had been receiving nasal continuous positive airway pressure (CPAP) intermittently for 17 days because of severe hyaline membrane disease and apnea. Ulceration and pressure necrosis of the septal mucosa preceded the perforation. Application of CPAP in the neonatal period should be considered as one of the differential diagnoses in infants with nasal septal perforation.

(Arch Otolaryngol 104:473, 1978)

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