• Latency-intensity (L-I) functions for (1) the auditory nerve action potential (AP) N1 peak, (2) the brain stem evoked response (BER) V peak, and (3) the N1-V interval were related to hearing level and lesion location. The AP L-I curves tended to steepen with increasing 4 to 8 kHz hearing level. This relationship was identical for cochlear and retrocochlear ears, except for a few retrocochlear ears with "inappropriate AP preservation." Both high-frequency cochlear loss and retrocochlear abnormality prolonged peak V latency, but retrocochlear abnormality generally prolonged it more. Among cochlear-loss ears, as 4 to 8 kHz hearing levels increased, N1-V intervals decreased and L-I curve slopes increased. In contrast, retrocochlear abnormality greatly prolonged N1-V intervals. As a retrocochlear sign, N1-V prolongation was slightly more reliable than V prolongation.
(Arch Otolaryngol 104:709-717, 1978)
Coats AC. Human Auditory Nerve Action Potentials and Brain Stem Evoked Responses: Latency-Intensity Functions in Detection of Cochlear and Retrocochlear Abnormality. Arch Otolaryngol. 1978;104(12):709–717. doi:10.1001/archotol.1978.00790120035006
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