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February 1979

Autografts of Uncrushed and Crushed Bone and Cartilage: Experimental Observations and Clinical Implications

Author Affiliations

From the Mayo Clinic and Mayo Foundation, Rochester, Minn.

Arch Otolaryngol. 1979;105(2):75-80. doi:10.1001/archotol.1979.00790140021004

• This study evaluated autografts of bone and cartilage, uncrushed and crushed, in the perichondrial space of the ear and subcutaneously in the paraspinal region in rabbits six weeks and six months after transplantation. The results support the belief that in a clinical setting it is important to preserve perichondrium because it facilitates growth of new cartilage. This study suggests that when autogenous tissue is to be used for subcutaneous augmentation, it is best to use crushed or uncrushed cartilage or uncrushed bone because they remain viable. In the perichondrial space, crushed and uncrushed cartilage grafts not only remain viable but also induce growth of new cartilage and bone. Autogenous crushed bone does not survive in the perichondrial space of the rabbit ear.

(Arch Otolaryngol 105:75-80, 1979)

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