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March 1979

Modification of Constant Optokinetic Nystagmus by Vestibular Stimulation

Author Affiliations

From the Division of Head and Neck Surgery (Otolaryngology) (Drs Jenkins, Honrubia, and Lau), Department of Neurology, Reed Neurological Research Center (Dr Baloh), and Department of Ophthalmology, Jules Stein Eye Institute (Dr Yee), UCLA School of Medicine, Los Angeles.

Arch Otolaryngol. 1979;105(3):132-136. doi:10.1001/archotol.1979.00790150022006

• Experiments were conducted to quantify the effect of a vestibular stimulation of known magnitude on a constant optokinetic nystagmus (OKN). Ten normal human subjects were tested with varying magnitudes of vestibular stimuli that were superimposed on a constant 30°/s optokinetic stimulus. The gain of the vestibular system in the dark was 0.42 ± 0.11, and the gain in the light during superimposition testing was 0.12 ± 0.02. From these results, predictions were made that the degree of vestibular imbalance necessary to produce an asymmetric OKN would generate a spontaneous nystagmus in the dark, which would be equivalent to 20 to 30°/s. Data from a large group of patients were used for corroboration of the results.

(Arch Otolaryngol 105:132-136, 1979)

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