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June 1980

Parapharyngeal Neoplasm of Mixed Mesenchymal and Neuroepithelial Origin

Author Affiliations

From the Department of Pathology (Dr Shuangshoti) and the Department of Ear, Nose, and Throat (Dr Chutchavaree), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Arch Otolaryngol. 1980;106(6):361-364. doi:10.1001/archotol.1980.00790300049010

• A 20-year-old man had a left parapharyngeal neoplasm that displayed features of sarcoma of the nerve sheath, meningioma with an osseous component, rhabdomyosarcoma, and ganglioneuroma. The diverse cellular population suggests a tumor origin from the ectomesenchymal remnants of the neural crest. The mesenchymal part of the crest would differentiate into a variety of mesenchymal neoplastic elements, and the neuroectodermal (neuroepithelial) portion into the ganglioneuroma. These various neoplastic constituents then would form a neoplasm of mixed mesenchymal and neuroepithelial origin, or an ectomesenchymoma.

(Arch Otolaryngol 106:361-364, 1980)

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