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March 1981

Malignant Fibrous Histiocytoma of the Nose and Nasopharynx

Author Affiliations

Radiation Therapy Section Department of Radiology; Radiation Research Laboratory Department of Radiology; Department of Otorhinolaryngology University of Iowa Hospital and Clinics Iowa City, IA 52242

Arch Otolaryngol. 1981;107(3):191. doi:10.1001/archotol.1981.00790390057016

Malignant fibrous histiocytoma (MFH) is a relatively newly described variety of soft-tissue sarcoma that rarely occurs in the nose, nasopharynx, and paranasal sinuses.

Report of a Case.—A 36-year-old man had an obstruction in his left nostril in September 1975. On examination, nasal polyps were found and a polypectomy was performed. A few weeks later the patient returned with a nasal obstruction in the same nostril. At this time, clinical and roentgenographic examinations revealed a nasopharyngeal soft-tissue mass, visible in the left nasal cavity, which involved the left ethmoid air cells. A biopsy specimen taken on Jan 20, 1976, indicated MFH. There were bilateral, rubbery, cervical lymph nodes that were larger on the left side. An external ethmoidectomy on the left side was performed to remove a necrotic soft-tissue mass. Postoperative radiation therapy was delivered to the nasopharynx, ethmoid sinuses, and both sides of the neck. The total tumor dose

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