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April 1981

Clinical Efficacy of Cefoxitin in the Treatment of Head and Neck Infections

Author Affiliations

From the Department of Medicine, Division of Infectious Diseases, George Washington University Medical Center, Washington, DC.

Arch Otolaryngol. 1981;107(4):242-244. doi:10.1001/archotol.1981.00790400044010

• Cefoxitin sodium, a new cephamycin antibiotic, is active against many aerobic and anaerobic bacteria. Four patients with infections of the head and neck (otitis externa with cellulitis, parotiditis, tracheitis, and facial cellulitis), who had failed to respond to initial antibiotic regimens, responded satisfactorily to cefoxitin therapy. No adverse effects were noted in any of these patients. Results of this report suggest cefoxitin is a safe and well-tolerated antibiotic that is efficacious in the treatment of head and neck bacterial infections that are sensitive to this drug.

(Arch Otolaryngol 1981;107:242-244)

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