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September 1981

Artificial Eustachian Tube-Induced Keratin Foreign-Body Granuloma

Author Affiliations

From the Temporal Bone Histopathology Laboratory, and the Departments of Otolaryngology and Pathology, University of Toronto.

Arch Otolaryngol. 1981;107(9):581-583. doi:10.1001/archotol.1981.00790450057019

• The pathogenesis of granulation tissue that arises periodically around artificial Eustachian tubes was elucidated by histologic examination of 15 cases of tube granuloma. All cases showed the presence of a keratin foreign-body granuloma. The implanted squames incited a foreign-body type of granulomatous reaction and produced a friable vascular exuberant mass that surrounded the artificial Eustachian tube. Histologically, the tube granuloma was characterized by the presence of irregular ovoid slit-like spaces that contained keratin squames, and it was surrounded by foreign-body giant cells.

(Arch Otolaryngol 1981;107:581-583)

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