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April 1982

The Ototoxicity of Topically Applied Povidone-Iodine Preparations

Author Affiliations

From the Department of Otolaryngology, University of Minnesota Medical School, Minneapolis.

Arch Otolaryngol. 1982;108(4):210-213. doi:10.1001/archotol.1982.00790520010004

• The ototoxicity of povidone-iodine solution and scrub, when topically applied to the round window of the chinchilla, was studied by means of compound action potentials. Povidone-iodine scrub has a greater ototoxic potential than povidone-iodine solution. One day after topical application of dilutions of 1% povidone-iodine solution, a 1:4 dilution showed a substantial ototoxic effect, while a 1:10 dilution did not.

(Arch Otolaryngol 1982;108:210-213)

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