• I evaluated the response of 200 patients undergoing office surgery to lowdose ketamine hydrochloride and diazepam as an adjunct to local anesthesia. In most patients, there was a slight increase in pulse rate and BP, but this was relatively mild. In almost all patients, there were no unpleasant recollections of the operative procedure, and I concluded that combination low-dose diazepam and ketamine is an effective and safe adjunct to local anesthesia in an office operating room facility.
(Arch Otolaryngol 1982;108:439-440)
Tobin HA. Low-Dose Ketamine and Diazepam: Use as an Adjunct to Local Anesthesia in an Office Operating Room. Arch Otolaryngol. 1982;108(7):439–440. doi:10.1001/archotol.1982.00790550043011
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