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September 1982

The Normal Chinchilla Round Window Membrane

Author Affiliations

From the Department of Otolaryngology, University of Minnesota Medical School, Minneapolis.

Arch Otolaryngol. 1982;108(9):550-554. doi:10.1001/archotol.1982.00790570016004

• The chinchilla round window membrane consists of three layers: (1) an outer epithelial layer facing the middle ear cavity with tight junctions and numerous desmosomes, (2) a middle connective-tissue layer consisting of fibroblasts, fibrocytes, collagen, elastin, capillaries, and myelinated and unmyelinated nerves, and (3) an inner cellular layer with thin cytoplasmic processes containing numerous micropinocytotic vesicles and dark granules similar in form to α-type glycogen. Studies of the fine structure of the normal round window membrane in animals are prerequisites to understanding the role of the round window membrane in both normal function and in diseased states such as otitis media.

(Arch Otolaryngol 1982;108:550-554)