In the last two decades, the technological progress in surgery and anesthesia, and in particular the skills and dedication of several head and neck surgeons, and radiotherapists, have made it possible to achieve local-regional control of disease in the majority of patients with carcinoma of the head and neck. In a series of patients with advanced carcinomas of the pyriform sinus reported in 1979 by Byers et al,1 from the M. D. Anderson Hospital in Houston, disease above the clavicles was controlled in as many as 81% of the patients. These results were obtained with the use of surgery and postoperative radiation therapy. Mesic et al,2 from the same institution, have recently reported their results in the treatment of lymphoepitheliomas of the nasopharynx with megalovoltage irradiation. The disease was successfully controlled above the clavicles in more than 90% of cases with advanced local (T3-T4) and cervical nodal (N2-N3)
MEDINA JE. The Controversial Role of BCG in the Treatment of Squamous Cell Carcinoma of the Head and Neck. Arch Otolaryngol. 1983;109(8):543. doi:10.1001/archotol.1983.00800220049012
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