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September 1983

Tissue Metabolism in Patients With Cancer

Author Affiliations

Liverpool, England

Arch Otolaryngol. 1983;109(9):634-635. doi:10.1001/archotol.1983.00800230070020

To the Editor.—In the November Archives (1982;108:697-699) Edström et al provided us with an important study in which they demonstrated an increased glucose utilization and turnover in malnourished patients with cancer when compared with malnourished patients free of malignant disease. Some aspects of this work, however, are open to criticism.

It is difficult to know what the authors mean by malnutrition, because no preliminary biochemical or anthropometric assessment of the nutritional state1 of the patients was given. It is therefore impossible to know how comparable the two groups were (those patients fed parenterally as opposed to those patients given enteral nutrition, or those patients with malignant neoplasms compared with those patients without). The 12 malnourished patients without cancer were matched with the 26 patients with cancer only with respect to age and activity. No data were given of previous food intake either before or after the onset of

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