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Article
January 1984

The Human Round Window Membrane: An Electron Microscopic Study

Author Affiliations

From the Department of Otolaryngology, University of Minnesota Medical School, Minneapolis.

Arch Otolaryngol. 1984;110(1):15-21. doi:10.1001/archotol.1984.00800270019005
Abstract

• The normal adult human round window membrane was examined by transmission electron microscopy. The membrane consists of the following three layers: (1) an outer squamous epithelial layer with an underlying basement membrane; (2) a middle fibrous layer containing collagen, elastin, fibrocytes, vessels, and nerves; and (3) an inner layer of mesothelial cells. Mucosal membrane veils that cover the round window membrane, forming "false" round window membranes, are also described. These membranes are also three layered, including (1) an outer epithelial layer with an underlying basement membrane, (2) a middle fibrous layer containing collagen, elastin, fibrocytes, vessels, and nerves, and (3) an inner epithelial layer with an underlying basement membrane. Ultrastructural differences between these two structures are discussed.

(Arch Otolaryngol 1984;110:15-21)

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