• Primidone has been reported to be effective in reducing tremor in patients with benign essential tremor. There is at least one report that suggests that the medication may reduce voice tremor, a frequent component of the essential tremor syndrome. Three patients with spastic dysphonia of essential (voice) tremor and one with more typical essential (voice) tremor were treated with primidone and experienced no alleviation in the voice signs. The side effects experienced by all patients were consistent with those noted in previous reports. Primidone does not seem to be effective in treating essential voice tremor or spastic dysphonia of essential voice tremor.
(Arch Otolaryngol 1984;110:394-397)
Hartman DE, Vishwanat B. Spastic Dysphonia and Essential (Voice) Tremor Treated With Primidone. Arch Otolaryngol. 1984;110(6):394–397. doi:10.1001/archotol.1984.00800320048011
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