• We transferred tumor tissue from two inverted schneiderian nasal papillomas to hypothymic nude mice. Tissue from one tumor, which later underwent malignant change, was transferred three times. Forty days lapsed before growth was evident, with a subsequent period of rapid growth. Histologic appearances of the primary tumor and xenografts were similar. Although the data are derived from only two cases, our findings suggest that the capacity of these tumors to grow in nude mice may be an index of their malignant potential.
(Arch Otolaryngol 1984;110:529-530)
Riglar C, Mackay IR, Burns GF, Dowling JP, Millar HS. Transfer of Human Nasal Papilloma Into Nude Mice. Arch Otolaryngol. 1984;110(8):529–530. doi:10.1001/archotol.1984.00800340041010
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.