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February 1985

Pharyngeal Wall CancerA Reappraisal After Comparison of Treatment Methods

Arch Otolaryngol. 1985;111(2):79-85. doi:10.1001/archotol.1985.00800040043003

• We retrospectively examined 89 patients with pharyngeal wall cancer treated in our institution between 1964 and 1981, to compare the results of treatment after low-dose preoperative irradiation and surgery (R + S) with those achieved with radiation therapy alone (RA). Age, sex, and stage of tumor were comparable for the 41 patients who had R + S and the 34 who had RA. Treatment outcome, survival, and tumor and nodal control were better for the R + S treatment group than for the RA treatment group. Patterns of relapse differed for the two treatment methods and suggested that each might complement the other. Low-dose preoperative irradiation and surgery more often controlled the pharyngeal tumor than did RA, while high-dose irradiation more often controlled nodal disease than did low-dose irradiation and surgery. Our experience suggests that surgical treatment combined with high doses of radiation might improve treatment results for pharyngeal wall cancer.

(Arch Otolaryngol 1985;111:79-85)