• Thirty-three patients with inoperable squamous cell carcinoma of the head and neck were treated with cisplatin, 15 mg/sq m, administered synchronously with high-dose radiation therapy. Twenty-nine patients (88%) responded to the regimen; of these, 20 had complete regression of all disease. Eight of the 20 had a relapse in less than one year of their treatment. Among those patients who did not have a relapse, the follow-up period was short. It is concluded that a clinical regression response is more likely with this treatment regimen than with radiation therapy alone, and that that response may be a better palliation. Further study of this combination of treatment modalities is warranted.
(Arch Otolaryngol 1985;111:114-118)
Leipzig B, Wetmore SJ, Putzeys R, Suen JY, Snyderman NL. Cisplatin Potentiation of Radiotherapy: Long-term Follow-up. Arch Otolaryngol. 1985;111(2):114–118. doi:10.1001/archotol.1985.00800040078011
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