• Acute, profound cisplatin-induced deafness has rarely been reported. Ototoxic reactions to cisplatin in the past have been subclinical, with most hearing loss occuring in the high-frequency range. A patient was treated with ultra-high-dose cisplatin who suffered acute profound deafness. Methods are suggested for preventing similar complications in other patients given cisplatin in high-dose ranges.
(Arch Otolaryngol 1985;111:344-345)
Guthrie TH, Gynther L. Acute Deafness: A Complication of High-Dose Cisplatin. Arch Otolaryngol. 1985;111(5):344–345. doi:10.1001/archotol.1985.00800070096018
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