• Cefazolin and moxalactam were compared in a prospective randomized double-blind trial of 118 patients undergoing oncologic head and neck surgery. Both antibiotics were given 2 g every four hours for four doses. Five infections were encountered in the cefazolin group (8.5%) and two infections in the moxalactam group (3.4%); this difference was not statistically significant. This assessment does not indicate, however, that the two regimens are equally efficacious.
(Arch Otolaryngol Head Neck Surg 1986;112:151-153)
Johnson JT, Yu VL, Myers EN, Wagner RL, Sigler BA. Cefazolin vs Moxalactam? A Double-blind Randomized Trial of Cephalosporins in Head and Neck Surgery. Arch Otolaryngol Head Neck Surg. 1986;112(2):151–153. doi:10.1001/archotol.1986.03780020031008
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